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multiplex fluorescent v2 rnascope in situ hybridization  (Advanced Cell Diagnostics Inc)

 
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    Advanced Cell Diagnostics Inc multiplex fluorescent v2 rnascope in situ hybridization
    Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and <t>RNASCOPE</t> analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.
    Multiplex Fluorescent V2 Rnascope In Situ Hybridization, supplied by Advanced Cell Diagnostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/multiplex fluorescent v2 rnascope in situ hybridization/product/Advanced Cell Diagnostics Inc
    Average 90 stars, based on 1 article reviews
    multiplex fluorescent v2 rnascope in situ hybridization - by Bioz Stars, 2026-05
    90/100 stars

    Images

    1) Product Images from "Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Reveals Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension"

    Article Title: Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Reveals Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension

    Journal: Journal of respiratory biology and translational medicine

    doi: 10.70322/jrbtm.2025.10004

    Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and RNASCOPE analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.
    Figure Legend Snippet: Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and RNASCOPE analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.

    Techniques Used: Marker, Immunostaining, RNAscope



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    Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and <t>RNASCOPE</t> analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.
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    Image Search Results


    Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and RNASCOPE analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.

    Journal: Journal of respiratory biology and translational medicine

    Article Title: Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Reveals Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension

    doi: 10.70322/jrbtm.2025.10004

    Figure Lengend Snippet: Spatial plot showing the change of EC subpopulation in PH mice. ( A ) Spatial plots showing the arterial ECs (AEC) and endothelial progenitor cells (EPC) were increased in KO mice ( n = 2). ( B ) Quantification of AECs and EPCs cell proportions in ( A ). ( C ) Spatial plots showing the general capillary ECs (CAP1) and aerocytes (CAP2) were reduced in KO mice ( n = 2). ( D ) Quantification data of AECs and EPCs in ( C ). ( E ) Spatial and Violin plots showing the increased AEC marker Sox17 , decreased CAP1 (gCap) marker Plvap , and decreased CAP2 (aCap) marker Prx in the KO mice ( n = 2). *** p < 0.001, **** p < 0.0001. ( F ) Immunostaining and RNASCOPE analysis validated the reduction of CAP2 ( Ednrb + /CD31 + ) in KO mice (WT n = 4, KO n = 3). * p < 0.05.

    Article Snippet: A Multiplex Fluorescent V2 RNAscope in situ hybridization (Advanced Cell Diagnostics, Newark, CA, USA) and immunostaining assay were conducted on lung cryosections obtained from mouse lung samples.

    Techniques: Marker, Immunostaining, RNAscope